I've discovered something amazing! Apart from developing carpal tunnel and horrible vision from many hours of using a mouse and keyboard, I have developed keyboard callus. Exhibit one: Korean Starcraft Players.
|Totally not being stereotypical... not all Koreans play Starcraft. Probably.|
|Notice the very prominent veins. The people at the blood center love me. I could probably be a very good druggie.|
I can probably guess you are confirming your own right now. Yes, your wrist has grown extra padding to accommodate for it setting against a hard surface all day. I wouldn't be surprised if my wrist bone has grown as well.